Advanced Light Microscopy and Spectroscopy Laboratory

Providing a unique collection of leading-edge optical microscopes, small-animal imaging devices, and fluorescent probes

Advanced Light Microscopy and Spectroscopy Laboratory


Leica DMI6000 Inverted Microscope

Main Use: Fast confocal scanning of live or fast moving specimens

The Leica DMI6000 inverted microscope for biomedical research offers Differential Interference Contrast (DICfor relief imaging of specimens with varying indices of refraction.

The intuitive, automated Leica DMI6000 is ideal for fluorescence, live cell, time-lapse imaging, high-speed multi-fluorescence optical sectioning, and micromanipulation.

The system features an automated contrast and illumination manager, motorized Z focus, parfocality function, automatic brightness and diaphragm adjustment, and many other automated functions that provide convenience and reproducible results.

For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

  • Yokogawa CSU-X1 spinning disk confocal scanner unit
  • Software controlled motorized stage and piezo-focusing device for 3-D sectioning
  • Andor EMCCD camera.
  • Solamere Technologies laser bank, computer, Yokogawa scanner and computer with running software.
  • Laser bank: 4 solid state lasers with excitation lines at 405 (dark blue) 491 (blue-green), 561 yellow-green)and 640 nm (far red).
  • Fast PC computer with over a terabyte of data storage space.
  • Running software: MicroManager opensource microscopy management software. Ultra-fast image acquisition (up to 1000 fps in full-frame) with minimal photobleaching and phototoxicity.